RET proto-oncogene mutations are restricted to codon 618 in Cypriot families with multiple endocrine neoplasia 2

Keyphrases

• Age of Onset 33%
• Allele Frequency 33%
• Biochemical Detection 33%
• Clinical Diagnosis 33%
• Clinical Presentation 33%
• Codon 100%
• Cypriot 100%
• Exon 10 33%
• Familial Medullary Thyroid Carcinoma 100%
• Families with multiples 100%
• Founder Effect 33%
• Genetic Modifiers 33%
• Germ Cells 33%
• Germline mutation 33%
• Inherited Cancer Syndrome 33%
• Multiple Endocrine Neoplasia Type 2 (MEN2) 100%
• Mutational Screening 33%
• No Significant Difference 33%
• Proband 100%
• RET Gene 33%
• RET mutation 33%
• RET Proto-oncogene 100%
• Uncommon mutation 33%
• Variant Allele Frequency 33%

Biochemistry, Genetics and Molecular Biology

• Codon 100%
• Exon 33%
• Founder Effect 33%
• Gene Frequency 66%
• Genetics 33%
• Germ Cell 33%
• Germline 33%
• Germline Mutation 33%
• Proband 100%
• RET Proto-Oncogene 100%