Abstract
Delta antigen (δ) is a transmissible agent requiring hepatitis B virus (HBV) for its replication. Antibody to δ (anti-δ) was present in nine of 71 (13%) British HBV carriers: six were intravenous drug abusers and two were haemophiliacs. Anti-δ was negative in 30 HBsAg positive homosexuals. Cirrhosis was common in patients with anti-δ and those with anti-δ positive cirrhosis were significantly younger than those with anti-δ negative cirrhosis. In British HBV carriers δ infection is associated with intravenous drug abuse and haemophilia and perhaps a more rapid progression of chronic liver disease.
Original language | English |
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Pages (from-to) | 1061-1063 |
Number of pages | 3 |
Journal | Gut |
Volume | 24 |
Issue number | 11 |
Publication status | Published - 1983 |