TY - JOUR
T1 - Surgical and hardware complications of deep brain stimulation. A seven-year experience and review of the literature
AU - Boviatsis, Efstathios J.
AU - Stavrinou, Lampis C.
AU - Themistocleous, Marios
AU - Kouyialis, Andreas T.
AU - Sakas, Damianos E.
PY - 2010/12
Y1 - 2010/12
N2 - Purpose Deep brain stimulation (DBS) has been established as a safe and efficient method for the treatment of various movement disorders. As the emerging applications continue to expand and more centers become eligible for the procedure, complication rates and complication avoidance become increasingly important. Our aim was to report the DBSrelated complication in our department over the last 7 years, compare our rates with those reported in the literature, and highlight those practices that will aid complications avoidance. Patients and methods Since 2003, 106 patients underwent DBS for various pathologies in our department. There were 38 (36%) females and 68 (64%) males with a mean age of 57 years. Preoperative diagnoses included Parkinson's disease (n=88), dystonia (n=12), tremor (n=3), epilepsy (n=1), obsessive-compulsive disorder (n=1), and central pain syndrome (n=1). Surgical and hardware-related complications, their treatment, and outcome were recorded and compared with those reported in the literature. Results There were 12 procedure-related complications (11.3% of patients, 5.7% of the procedures). These included death (n=1), aborted procedure (n=1), postoperative respiratory distress (n=3), intracranial hemorrhage (n=2), epilepsy (n=1), postoperative confusion or agitation (n=3), and malignant neuroleptic syndrome (n=1). Hardwarerelated complications presented in 4.3% of the procedures and included infection (five patients, 4.7%), electrode breakage (0.94%), lead migration or misplacement (0.94%), and stricture formation (two patients, 1.9%). Conclusions Complication rates after DBS surgery remain low, proving that DBS is not only effective but also safe. Certain strategies do exist in order to minimize complications.
AB - Purpose Deep brain stimulation (DBS) has been established as a safe and efficient method for the treatment of various movement disorders. As the emerging applications continue to expand and more centers become eligible for the procedure, complication rates and complication avoidance become increasingly important. Our aim was to report the DBSrelated complication in our department over the last 7 years, compare our rates with those reported in the literature, and highlight those practices that will aid complications avoidance. Patients and methods Since 2003, 106 patients underwent DBS for various pathologies in our department. There were 38 (36%) females and 68 (64%) males with a mean age of 57 years. Preoperative diagnoses included Parkinson's disease (n=88), dystonia (n=12), tremor (n=3), epilepsy (n=1), obsessive-compulsive disorder (n=1), and central pain syndrome (n=1). Surgical and hardware-related complications, their treatment, and outcome were recorded and compared with those reported in the literature. Results There were 12 procedure-related complications (11.3% of patients, 5.7% of the procedures). These included death (n=1), aborted procedure (n=1), postoperative respiratory distress (n=3), intracranial hemorrhage (n=2), epilepsy (n=1), postoperative confusion or agitation (n=3), and malignant neuroleptic syndrome (n=1). Hardwarerelated complications presented in 4.3% of the procedures and included infection (five patients, 4.7%), electrode breakage (0.94%), lead migration or misplacement (0.94%), and stricture formation (two patients, 1.9%). Conclusions Complication rates after DBS surgery remain low, proving that DBS is not only effective but also safe. Certain strategies do exist in order to minimize complications.
KW - Complication avoidance
KW - Deep brain stimulation
KW - Hardware complications
KW - Neuroleptic malignant syndrome
KW - Surgical complications
UR - http://www.scopus.com/inward/record.url?scp=78651111094&partnerID=8YFLogxK
U2 - 10.1007/s00701-010-0749-8
DO - 10.1007/s00701-010-0749-8
M3 - Article
C2 - 20658301
AN - SCOPUS:78651111094
SN - 0001-6268
VL - 152
SP - 2053
EP - 2062
JO - Acta Neurochirurgica
JF - Acta Neurochirurgica
IS - 12
ER -