Synthesis of a protected δ-glyco-amino acid building block for incorporation into peptide chains

George Paloumbis; Christos C. Petrou; Berthold Nock; Theodosia Maina; George Pairas; Petros G. Tsoungas; Paul Cordopatis

doi:10.1055/s-2007-965942

Synthesis of a protected δ-glyco-amino acid building block for incorporation into peptide chains

George Paloumbis
, Christos C. Petrou
, Berthold Nock
, Theodosia Maina
, George Pairas
, Petros G. Tsoungas
, Paul Cordopatis

School of Life and Health Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

The synthesis of a suitably protected sugar amino acid (δ-glyco-amino acid) as a building block to be incorporated into the peptide chain (N-terminus) of bioactive peptide analogues is described. Its efficient coupling reactions with pilot amino acids as well as dipeptides have been accomplished by standard peptide chemistry.

Original language	English
Pages (from-to)	845-852
Number of pages	8
Journal	Synthesis
Issue number	6
DOIs	https://doi.org/10.1055/s-2007-965942
Publication status	Published - 16 Mar 2007

Keywords

δ-glyco-amino acid
Carbohydrates
Glycopeptides
Glycosylation
Radiolabelling

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10.1055/s-2007-965942

Cite this

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title = "Synthesis of a protected δ-glyco-amino acid building block for incorporation into peptide chains",

abstract = "The synthesis of a suitably protected sugar amino acid (δ-glyco-amino acid) as a building block to be incorporated into the peptide chain (N-terminus) of bioactive peptide analogues is described. Its efficient coupling reactions with pilot amino acids as well as dipeptides have been accomplished by standard peptide chemistry.",

keywords = "δ-glyco-amino acid, Carbohydrates, Glycopeptides, Glycosylation, Radiolabelling",

author = "George Paloumbis and Petrou, \{Christos C.\} and Berthold Nock and Theodosia Maina and George Pairas and Tsoungas, \{Petros G.\} and Paul Cordopatis",

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T1 - Synthesis of a protected δ-glyco-amino acid building block for incorporation into peptide chains

AU - Paloumbis, George

AU - Petrou, Christos C.

AU - Nock, Berthold

AU - Maina, Theodosia

AU - Pairas, George

AU - Tsoungas, Petros G.

AU - Cordopatis, Paul

PY - 2007/3/16

Y1 - 2007/3/16

N2 - The synthesis of a suitably protected sugar amino acid (δ-glyco-amino acid) as a building block to be incorporated into the peptide chain (N-terminus) of bioactive peptide analogues is described. Its efficient coupling reactions with pilot amino acids as well as dipeptides have been accomplished by standard peptide chemistry.

AB - The synthesis of a suitably protected sugar amino acid (δ-glyco-amino acid) as a building block to be incorporated into the peptide chain (N-terminus) of bioactive peptide analogues is described. Its efficient coupling reactions with pilot amino acids as well as dipeptides have been accomplished by standard peptide chemistry.

KW - δ-glyco-amino acid

KW - Carbohydrates

KW - Glycopeptides

KW - Glycosylation

KW - Radiolabelling

UR - https://www.scopus.com/pages/publications/33947575627

U2 - 10.1055/s-2007-965942

DO - 10.1055/s-2007-965942

M3 - Article

AN - SCOPUS:33947575627

SN - 0039-7881

SP - 845

EP - 852

JO - Synthesis

JF - Synthesis

IS - 6

ER -

Synthesis of a protected δ-glyco-amino acid building block for incorporation into peptide chains

Abstract

Keywords

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