Synthesis of triazole-functionalized 2-DOS analogues and their evaluation as A-site binders

Keyphrases

• Binder 100%
• A-site 100%
• 2-deoxystreptamine 100%
• Triazole 100%
• Biological Function 50%
• Regioselective Functionalization 50%
• Binding Potency 50%
• Antibacterial Ability 50%
• Molecular Frameworks 50%
• Orthogonal Protection 50%
• Aminoglycoside Antibiotics 50%
• Biological Evaluation 50%

Chemistry

• 2-Deoxystreptamine 100%
• Triazole 100%
• RNA 50%
• Aminoglycoside Antibiotic Agent 50%