TY - JOUR
T1 - The Burden of Gout and Its Attributable Risk Factors in the Middle East and North Africa Region, 1990 to 2019
AU - Amiri, Fatemeh
AU - Kolahi, Ali Asghar
AU - Nejadghaderi, Seyed Aria
AU - Noori, Maryam
AU - Khabbazi, Alireza
AU - Sullman, Mark J.M.
AU - Kaufman, Jay S.
AU - Collins, Gary S.
AU - Safiri, Saeid
N1 - Publisher Copyright:
Copyright © 2023 by the Journal of Rheumatology.
PY - 2023/1/1
Y1 - 2023/1/1
N2 - OBJECTIVE: This study reported the burden of gout and its attributable risk factors in the Middle East and North Africa (MENA) region between 1990 and 2019 by age, sex, and sociodemographic index (SDI). METHODS: Data on the prevalence, incidence, and years lived with disability (YLD) due to gout were obtained from the Global Burden of Disease 2019 study for the 21 countries in the MENA region, from 1990 to 2019. RESULTS: In 2019, the regional age-standardized point prevalence and annual incidence rates of gout were 509.1 and 97.7 per 100,000 population, which represent a 12% and 11.1% increase since 1990, respectively. Moreover, in 2019 the regional age-standardized YLD rate was 15.8 per 100,000 population, an 11.7% increase since 1990. In 2019, Qatar and Afghanistan had the highest and lowest age-standardized YLD rates, respectively. Regionally, the age-standardized point prevalence of gout increased with age up to the oldest age group, and it was more prevalent among males in all age groups. In addition, there was an overall positive association between SDI and the burden of gout between 1990 and 2019. In 2019, high BMI (46.1%) was the largest contributor to the burden of gout in the MENA region. CONCLUSION: There were large intercountry variations in the burden of gout, but in general, it has increased in MENA over the last 3 decades. This increase is in line with the global trends of gout. However, the age-standardized YLD rate change was higher in MENA than at the global level.
AB - OBJECTIVE: This study reported the burden of gout and its attributable risk factors in the Middle East and North Africa (MENA) region between 1990 and 2019 by age, sex, and sociodemographic index (SDI). METHODS: Data on the prevalence, incidence, and years lived with disability (YLD) due to gout were obtained from the Global Burden of Disease 2019 study for the 21 countries in the MENA region, from 1990 to 2019. RESULTS: In 2019, the regional age-standardized point prevalence and annual incidence rates of gout were 509.1 and 97.7 per 100,000 population, which represent a 12% and 11.1% increase since 1990, respectively. Moreover, in 2019 the regional age-standardized YLD rate was 15.8 per 100,000 population, an 11.7% increase since 1990. In 2019, Qatar and Afghanistan had the highest and lowest age-standardized YLD rates, respectively. Regionally, the age-standardized point prevalence of gout increased with age up to the oldest age group, and it was more prevalent among males in all age groups. In addition, there was an overall positive association between SDI and the burden of gout between 1990 and 2019. In 2019, high BMI (46.1%) was the largest contributor to the burden of gout in the MENA region. CONCLUSION: There were large intercountry variations in the burden of gout, but in general, it has increased in MENA over the last 3 decades. This increase is in line with the global trends of gout. However, the age-standardized YLD rate change was higher in MENA than at the global level.
KW - global burden of disease
KW - gout
KW - incidence
KW - Middle East and North Africa
KW - prevalence
KW - risk factor
KW - years lived with disability
UR - http://www.scopus.com/inward/record.url?scp=85145343966&partnerID=8YFLogxK
U2 - 10.3899/jrheum.220425
DO - 10.3899/jrheum.220425
M3 - Article
C2 - 36455948
AN - SCOPUS:85145343966
SN - 0315-162X
VL - 50
SP - 107
EP - 116
JO - The Journal of rheumatology
JF - The Journal of rheumatology
IS - 1
ER -