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The platelet receptor CLEC-2 is active as a dimer
Aleksandra A. Watson
, Charita M. Christou
, John R. James
, Angharad E. Fenton-May
, Gerald E. Moncayo
, Anita R. Mistry
, Simon J. Davis
, Robert J C Gilbert
, Aron Chakera
, Chris A. O'Callaghan
School of Life and Health Sciences
University of Oxford
University of California at San Francisco
Division of Structural Biology
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Keyphrases
Analytical Ultracentrifugation
20%
Bioluminescence Resonance Energy Transfer
20%
C-type Lectin-like Receptor 2
100%
Disulfide
20%
Downstream Signaling
20%
Gel Filtration Chromatography
20%
Homodimer
20%
Immunoreceptor Tyrosine-based Activation Motif
20%
Intracellular Domain
20%
Multi-angle Light Scattering
20%
Phosphorylation
40%
Platelet Activation
20%
Platelet Aggregation
20%
Platelet Receptors
100%
Podoplanin
20%
Recombinant Protein Production
20%
Rhodocytin
20%
Signaling Events
20%
Snake Venom
20%
Spleen Tyrosine Kinase
60%
Surface Plasmon Resonance
20%
Surface Proteins
20%
Tumor Cells
20%
Tyrosine
20%
Tyrosine Residue
20%
Western Blotting
20%
Biochemistry, Genetics and Molecular Biology
Bioluminescence
33%
Cell Surface Protein
33%
Disulfide
33%
Energy Transfer
33%
Gel Permeation Chromatography
33%
Immunoreceptor Tyrosine-Based Activation Motif
33%
Janus Kinase 1
100%
Light Scattering
33%
Platelet
100%
Protein Expression
33%
Recombinant Protein
33%
Surface Plasmon Resonance
33%
Thrombocyte Activation
33%
Thrombocyte Aggregation
33%
Tyrosine
66%
Ultracentrifugation
33%
Western Blotting
33%