The removal of hepatitis B virus from factor VIII concentrates by fractionation on ethylene maleic anhydride polyelectrolyte

S. A. Galpin, P. Karayiannis, S. M. Middleton, H. C. Thomas

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)

Abstract

Chromatography with a solid‐phase polyelectrolyte based on ethylene maleic anhydride polyelectrolyte (EMA PE) has been shown to remove a large proportion of hepatitis B surface antigen (HBsAg), including hepatitis B virus (HBV) particles, from contaminated cryoprecipitate. This process may reduce the risk of transmission of HBV infection when factor VIII concentrates are administered.

Original languageEnglish
Pages (from-to)229-233
Number of pages5
JournalJournal of Medical Virology
Volume14
Issue number3
DOIs
Publication statusPublished - 1984

Keywords

  • cryoprecipitate
  • factor VIII
  • polyelectrolyte
  • viral hepatitis

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