Abstract
General anaesthesia is a reversible state whereby conscious experience is disrupted and reflexes to afferent stimuli are depressed. The precise method of action of anaesthetic agents is still largely unknown. However, the administration of anaesthetics causes observable changes in the electrical brain activity (EEG), the study of which can provide an insight into the mechanism of action of general anaesthesia. This paper investigates the patterns of bidirectional interactions that are manifest in brain activity during anaesthetic induction with propofol. Granger Causality is applied to the EEG of patients scheduled for surgery under general anaesthesia as a means of characterising the interactions between different brain areas prior and after the administration of the anaesthetic agents. Strong unidirectional information flow between frontal and posterior areas was found to occur shortly after anaesthetic induction.
Original language | English |
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Title of host publication | BIOSIGNALS 2011 - Proceedings of the International Conference on Bio-Inspired Systems and Signal Processing |
Pages | 188-194 |
Number of pages | 7 |
Publication status | Published - 18 Jul 2011 |
Externally published | Yes |
Event | International Conference on Bio-Inspired Systems and Signal Processing, BIOSIGNALS 2011 - Rome, Italy Duration: 26 Jan 2011 → 29 Jan 2011 |
Conference
Conference | International Conference on Bio-Inspired Systems and Signal Processing, BIOSIGNALS 2011 |
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Country/Territory | Italy |
City | Rome |
Period | 26/01/11 → 29/01/11 |
Keywords
- Anaesthesia monitoring
- Bidirectional interaction
- Electroencephalogram
- Granger causality
- Synchronisation