ZNF232: Structure and expression analysis of a novel human C2H2 zinc finger gene, member of the SCAN/LeR domain subfamily

  • Lampros A. Mavrogiannis
  • , Alexandros Argyrokastritis
  • , Nicholas Tzitzikas
  • , Emmanuel Dermitzakis
  • , Theologia Sarafidou
  • , Philippos C. Patsalis
  • , Nicholas K. Moschonas

Research output: Contribution to journalArticlepeer-review

Abstract

We have identified a novel zinc finger gene, ZNF232, mapped to human chromosome 17p12. The coding region of the gene is organized in three exons corresponding to a 417 amino acid long polypeptide containing a SCAN/LeR domain and five C2H2-type zinc fingers. ZNF232 is possibly a nuclear protein, as suggested by expression analysis of GFP/ZNF232 chimeric constructs. ZNF232 transcripts were detected in a wide collection of adult human tissues. The gene is possibly subjected to tissue-specific post-transcriptional regulation by means of alternative splicing.

Original languageEnglish
Pages (from-to)300-305
Number of pages6
JournalBiochimica et Biophysica Acta - Gene Structure and Expression
Volume1518
Issue number3
DOIs
Publication statusPublished - 16 Apr 2001
Externally publishedYes

Keywords

  • Chromosome 17
  • Human erythroleukemia K562 cell
  • Normalized cDNA library
  • Nucleus
  • SCAN/LeR domain
  • Zinc finger protein

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